Cold Agglutinin Disease market Size, Share, Growth, Segment, Trends,Technologies, Investment Opportunities and Forecast

4 min readSep 21, 2023


Market Analysis and Size

In recent years, the cold agglutinin disease market is anticipated to grow rapidly during the forecast period. Cold agglutinin disease (CAD) is an uncommon subset of autoimmune haemolytic anaemia that affects clonal B-cell lymphoproliferative cells (AIHA). CAD occurs for 15–25 percent of AIHA and primarily affects middle-aged and elderly people. When bone marrow-derived clonal B lymphocytes are exposed to freezing temperatures (0–4°C), they produce autoantibodies that attach to erythrocytes, producing agglutination and eventually immune-mediated haemolysis.

Data Bridge Market Research analyses that the cold agglutinin disease market was valued at USD 72 million in 2021 and is expected to reach USD 293.46 million by 2029, registering a CAGR of 19.20% during the forecast period of 2022 to 2029. The market report curated by the Data Bridge Market Research team includes in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Data Bridge Market research has a newly released expansive study titled “Cold Agglutinin Disease Market” which guarantees you will remain better informed than your competition. This study provides a broader perspective of the marketplace with its comprehensive market insights and analysis which eases surviving and success in the market.

Market Definition

Cold agglutinin disease is a rare type of acquired autoimmune haemolytic anaemia in which the body’s immune system attacks and destroys its own red blood cells due to exposure to cold temperatures. Cold temperatures or viral infections can trigger or worsen symptoms of cold agglutinin disease (CAD), and most people with the disease experience haemolytic anaemia symptoms such as fatigue, cold hands and feet, dizziness, headaches, pale skin, dark urine, jaundice, chest pain, back pain, leg pain, diarrhoea, heart problems and vomiting.

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Some of the major players operating in the cold agglutinin disease market are:

  • F. Hoffmann-La Roche Ltd. (Switzerland)
  • Mylan N.V. (US)
  • Teva Pharmaceutical Industries Ltd.(Israel)
  • Sanofi (France)
  • Pfizer Inc. (US)
  • GlaxoSmithKline plc (UK)
  • Novartis AG (Switzerland)
  • Zydus Cadila (India)
  • AstraZeneca (UK)
  • Johnson & Johnson (US)
  • Bayer AG (Germany)
  • Sun Pharmaceutical Industries Ltd. (India)
  • Apellis Pharmaceuticals (US)
  • Incyte Corporation (US)
  • Fresenius Kabi AG (Germany)
  • Amgen Inc. (US)
  • Bristol-Myers Squibb Company (US)
  • AbbVie Inc. (US)
  • Eli Lilly and Company (US)
  • Merck KGaA (Germany)


  • Increase in the number of research and development activities

Moreover, the market’s growth is fueled by an increase in the number of research and development activities. This will provide beneficial opportunities for the cold agglutinin disease market growth. Along with this, rising drug approvals and launches will further propel the market’s growth rate.

Moreover, rising investment for the development of advanced technologies and increase in the number of emerging markets will further provide beneficial opportunities for the cold agglutinin disease market growth during the forecast period.

To achieve noteworthy business growth and maximum return on investment (ROI), adopting supreme this market research report is truly beneficial. The report comprises of most-detailed market segmentation, systematic analysis of major market players, trends in consumer and supply chain dynamics, and insights about new geographical markets. This market report has been framed by taking into account several factors of the present and upcoming market scenario. Statistical and numerical data covered in the report is represented using graphs and tables which simplify the understanding of facts and figures.

The analysis and estimations carried out via this market analysis report helps to get the details about the product launches, future products, joint ventures, marketing strategy, developments, mergers and acquisitions and effect of the same on sales, marketing, promotions, revenue, import, export, and CAGR values. The report assists in determining and optimizing each stage in the lifecycle of industrial process that includes engagement, acquisition, retention, and monetization. An international this market report contains most recent and efficient market insights with which businesses can ponder to augment their marketing, advertising, promotional and sales strategies.

Core Objective of the This Market:

  • This Market Size and growth rate factors.
  • Important changes in the future this Market.
  • Top worldwide competitors of the Market.
  • Scope and product outlook of This Market.
  • Developing regions with potential growth in the future.
  • Tough Challenges and risk faced in Market.
  • Global top manufacturers profile and sales statistics.

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